Regulation of the insulin-like growth factor 2 gene is central to the mechanisms used by cancer cells to sustain their proliferative and aggressive behavior. A new peer-reviewed article gives us an updated view of the underlying molecular mechanisms in a special issue of Biomedicines which we contributed as ISOPROG-Somatolink research…
We thank the editorial board of the “Cell Cycle” journal (*) for the publication of our review article entitled “Cell Cycle Control by the Insulin-like Growth Factor Signal: At the Crossroad between Cell Growth and Mitotic Regulation”. (*)https://www.tandfonline.com/…/10…/15384101.2022.2108117). Peer reviewers have defined it, respectively, “a remarkable piece of work” and…
A review based on our published work surrounding the control of the oncogenic protein EphB4 by the cancer secreted and self-stimulating factor IGF-II has been conveyed on the peer review article published on the Journal “Critical Reviews in Eukariotic Expression”. The article highlights the key points of our discoveries and…
Oncogenomics features of Melanoma play a key part in personalized cancer bio-profiling and treatment strategies. We have conveyed the scientific advances in our molecular understanding of this disease with specific focus on the intracellular abnormalities linked to target therapies and the role of the tumor microenvironment in this article published…
A novel cancer cell regulatory mechanism functionally linking the cancer cell secreted factor IGF-II and the self-stimulating signal leading to the steady over-expression of EphB4 in the same cells has been unfolded in the article published on the prestigious journal “Oncogene” (Nature Publishing Group) [Impact Factor 7.99]. The article discloses…