Regulation of the insulin-like growth factor 2 gene is central to the mechanisms used by cancer cells to sustain their proliferative and aggressive behavior. A new peer-reviewed article gives us an updated view of the underlying molecular mechanisms in a special issue of Biomedicines which we contributed as ISOPROG-Somatolink research…
A review based on our published work surrounding the control of the oncogenic protein EphB4 by the cancer secreted and self-stimulating factor IGF-II has been conveyed on the peer review article published on the Journal “Critical Reviews in Eukariotic Expression”. The article highlights the key points of our discoveries and…
EphB4 is a blood vessel stimulatory factor over-expressed in human cancer cells but little has been known as for the factors regulating its gene expression. Such information can be derived in good part by the sequence and structure of each gene “promoter”region. In this work our team has reconstructed, sequenced…