Over-expression by degradation rescue of RTKs via cancer-secreted autocrine growth factors: a Phospho-degron-driven actionable layer of post-translational regulation?

The relationship between receptors tyrosine kinases (RTKs) overexpression in cancer by growth-factors signaling and Degron domains has been addressed in the peer-reviewed article entitled: “Over-expression by degradation rescue of RTKs via cancer-secreted autocrine growth factors: a Phospho-degron-driven actionable layer of post-translational regulation?” In this peer-reviewed perspective article authored by the…

Continue reading